Symbol
Name
ID

Htr1a
5-hydroxytryptamine (serotonin) receptor 1A
MGI:96273

Phenotype annotations related to behavior/neurological

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes	Addictive alcohol use
Disease(s) Associated with HTR1A	Addictive alcohol use
alcohol dependence

Mouse Phenotypes

behavior/neurological phenotype

increased susceptibility to pharmacologically induced seizures

abnormal spatial learning

behavioral despair

increased anxiety-related response

increased thigmotaxis

decreased vertical activity

increased locomotor activity

abnormal sleep duration

abnormal sleep pattern

increased slow-wave sleep duration

increased frequency of paradoxical sleep

fragmentation of sleep/wake states

Availability

Mouse Genotype

Htr1a^tm1Rhn/Htr1a^tm1Rhn

Htr1a^tm1Tct/Htr1a^tm1Tct

Htr1a^tm1Toth/Htr1a^tm1Toth

Htr1a^tm1Rhn/Htr1a⁺

Htr1a^tm1Tct/Htr1a⁺

Htr1a^tm1Toth/Htr1a⁺

Htr1a^tm2Rhn/Htr1a⁺

Htr1a^tm3.1Rhn/?
Tg(HCRT-tTA)G5Ahky/0

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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