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Symbol Name ID |
Gria1
glutamate receptor, ionotropic, AMPA1 (alpha 1) MGI:95808 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Feeding difficulties |
Self-injurious behavior |
| Disease(s) Associated with GRIA1 | ||
| autosomal recessive intellectual developmental disorder 76 |
| Mouse Phenotypes | behavior/neurological phenotype |
abnormal behavioral response to xenobiotic |
decreased behavioral withdrawal response |
abnormal associative learning |
enhanced conditioned place preference behavior |
impaired contextual conditioning behavior |
impaired cued conditioning behavior |
abnormal response to new environment |
decreased exploration in new environment |
increased exploration in new environment |
abnormal long-term spatial reference memory |
abnormal spatial working memory |
abnormal emotion/affect behavior |
decreased aggression towards male mice |
decreased anxiety-related response |
increased anxiety-related response |
abnormal freezing behavior |
decreased freezing behavior |
decreased startle reflex |
abnormal locomotor behavior |
abnormal gait |
decreased vertical activity |
increased vertical activity |
increased locomotor activity |
hyperactivity |
induced hyperactivity |
decreased chemical nociceptive threshold |
increased mechanical nociceptive threshold |
abnormal nociception after inflammation |
hypoalgesia |
abnormal sexual interaction |
abnormal social investigation |
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| Availability | Mouse Genotype | ||||||||||||||||||||||||||||||||
| Gria1em1(IMPC)H/Gria1em1(IMPC)H | |||||||||||||||||||||||||||||||||
| Gria1em1(IMPC)Hmgu/Gria1em1(IMPC)Hmgu | |||||||||||||||||||||||||||||||||
| Gria1tm1Erk/Gria1tm1Erk | * | ||||||||||||||||||||||||||||||||
| Gria1tm1Lex/Gria1tm1Lex | |||||||||||||||||||||||||||||||||
| Gria1tm1Rlh/Gria1tm1Rlh | |||||||||||||||||||||||||||||||||
| Gria1tm1Rsp/Gria1tm1Rsp | * | ||||||||||||||||||||||||||||||||
| Gria1tm5Rlh/Gria1tm5Rlh | |||||||||||||||||||||||||||||||||
| Gria1tm2Rsp/Gria1tm2Rsp Tg(Pvalb-cre)1Mony/0 (conditional) |
* | ||||||||||||||||||||||||||||||||
| Gria1tm2Rsp/Gria1tm2Rsp Tg(Slc6a3-icre)9075Gsc/0 (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/30/2024 MGI 6.23 |
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