Symbol
Name
ID

Gja1
gap junction protein, alpha 1
MGI:95713

Phenotype annotations related to growth/size/body

Darker colors indicate more annotations

Human Phenotypes	Umbilical hernia	Short stature	Failure to thrive	Weight loss
Disease(s) Associated with GJA1	Umbilical hernia	Short stature	Failure to thrive	Weight loss
erythrokeratodermia variabilis
oculodentodigital dysplasia

Mouse Phenotypes

heart right ventricle hypertrophy

small frontal bone

abnormal jaw morphology

abnormal alveolar process morphology

abnormal tooth morphology

abnormal incisor morphology

small lower incisors

abnormal tooth development

abnormal tooth hard tissue morphology

reduced enamel thickness

brittle teeth

small mandible

small maxilla

abnormal nasal bone morphology

small nasal bone

short zygomatic bone

abnormal facial morphology

small face

depressed nasal bridge

pointed snout

small snout

abnormal head shape

abnormal embryo size

ovary cyst

decreased birth weight

decreased birth body size

decreased body weight

abnormal head size

microcephaly

decreased body size

postnatal growth retardation

Availability

Mouse Genotype

Gja1^{em1(IMPC)Ccpcz}/Gja1^{em1(IMPC)Ccpcz}

Gja1^em1Ipche/Gja1^em1Ipche

Gja1^tm1Kdr/Gja1^tm1Kdr

Gja1^tm1Kdr/Gja1^tm1Kdr
Tg(CMV-Gja1)BClo/0

Gja1^tm7(Gja2)Kwi/Gja1^tm7(Gja2)Kwi

Tg(CMV-Gja1)BClo/Tg(CMV-Gja1)BClo

Gja1^M1Jrt/Gja1⁺

Gja1^tm1Dlg/Gja1^tm1Dlg
Tg(GFAP-cre)1Kdmc/0 (conditional)

Gja1^tm1Gfi/Gja1^tm1.1Gfi
Tg(Pax3-cre)1Joe/0 (conditional)

Gja1^tm8Kwi/Gja1⁺
Tg(Pgk1-cre)1Lni/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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