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Symbol Name ID |
Ghr
growth hormone receptor MGI:95708 |
| Darker colors indicate more annotations |
| Human Phenotypes | Abnormal skull morphology |
Micrognathia |
Genu valgum |
Short toe |
Brachydactyly |
Abnormality of the elbow |
Limb undergrowth |
Tendon xanthomatosis |
Delayed skeletal maturation |
Short long bone |
Abnormal joint morphology |
Osteoarthritis |
| Disease(s) Associated with GHR | ||||||||||||
| familial hypercholesterolemia | ||||||||||||
| isolated growth hormone deficiency | ||||||||||||
| Laron syndrome |
| Mouse Phenotypes | short femur |
short tibia |
abnormal long bone epiphyseal plate morphology |
abnormal long bone epiphyseal plate proliferative zone |
abnormal long bone hypertrophic chondrocyte zone |
decreased width of hypertrophic chondrocyte zone |
decreased length of long bones |
decreased bone mineral content |
decreased areal bone mineral density |
decreased bone mineral density |
abnormal compact bone morphology |
abnormal trabecular bone morphology |
abnormal chondrocyte morphology |
abnormal skeleton development |
abnormal bone ossification |
delayed endochondral bone ossification |
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| Availability | Mouse Genotype | ||||||||||||||||
| Ghrtm1.1Jero/Ghrtm1.1Jero | |||||||||||||||||
| Ghrtm1Arge/Ghrtm1Arge | |||||||||||||||||
| Ghrtm1Jjk/Ghrtm1Jjk | |||||||||||||||||
| Ghrtm1.1Masp/Ghrtm1.1Masp Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+ (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/30/2024 MGI 6.23 |
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