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Symbol
Name
ID

Gad2
glutamic acid decarboxylase 2
MGI:95634

Phenotype annotations related to behavior/neurological

!	Indicates phenotype varies with strain background.
	Darker colors indicate more annotations

Human Phenotypes	Negativism	Polydipsia	Polyphagia	Addictive alcohol use
Disease(s) Associated with GAD2	Negativism	Polydipsia	Polyphagia	Addictive alcohol use
alcohol dependence
schizophrenia
type 1 diabetes mellitus

Mouse Phenotypes

abnormal behavior

decreased exploration in new environment

decreased aggression towards male mice

increased coping response

increased anxiety-related response

increased thigmotaxis

increased vertical activity

decreased locomotor activity

seizures

myoclonus

tonic-clonic seizures

Availability

Mouse Genotype

Gad2^{tm1b(EUCOMM)Wtsi}/Gad2^{tm1b(EUCOMM)Wtsi}

Gad2^tm1Bae/Gad2^tm1Bae

!

Gad2^tm1Miya/Gad2^tm1Miya

Gad2^tm1Oba/Gad2^tm1Oba

Gad2^tm1Oba/Gad2⁺

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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