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Symbol
Name
ID
Gad1
glutamate decarboxylase 1
MGI:95632
Phenotype annotations related to behavior/neurological
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Negativism
Addictive alcohol use
Disease(s) Associated with GAD1
alcohol dependence
schizophrenia

Mouse Phenotypes
behavior/neurological phenotype
abnormal behavioral response to amphetamine
enhanced cued conditioning behavior
abnormal response to novel odor
absent gastric milk in neonates
abnormal suckling behavior
decreased anxiety-related response
slow extinction of fear memory
abnormal response to novel object
abnormal involuntary movement
increased startle reflex
limb grasping
abnormal motor coordination/balance
impaired coordination
decreased grip strength
abnormal gait
decreased vertical activity
increased vertical activity
decreased locomotor activity
abnormal social investigation
Availability Mouse Genotype
Gad1tm1Mrc/Gad1tm1Mrc
Gad1tm1Oba/Gad1tm1Oba *
Gad1tm1Tama/Gad1tm1Tama
Tg(Cck-EGFP/RNAi:Gad1)2Mirn/?
Tg(Cnr1-EGFP/RNAi:Gad1)1Mirn/?
Tg(Npy-EGFP/RNAi:Gad1)1Mirn/?
Tg(Pvalb-tdTomato/RNAi:Gad1)3Mirn/?
Gad1tm2Oba/Gad1tm2Oba
Ptf1atm1.1(cre)Cvw/Ptf1a+  (conditional)
Drd1tm1(cre)Rpa/Drd1+
Gad1tm1Rpa/Gad1tm1.1Rpa  (conditional)
*

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory