Symbol
Name
ID

Gabrb3
GABRB3, gamma-aminobutyric acid type A receptor subunit beta 3
MGI:95621

Phenotype annotations related to behavior/neurological

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes	Hyperactivity	Attention deficit hyperactivity disorder	Impulsivity
Disease(s) Associated with GABRB3
developmental and epileptic encephalopathy 43

Mouse Phenotypes

behavior/neurological phenotype

abnormal behavior

increased susceptibility to pharmacologically induced seizures

impaired behavioral response to xenobiotic

enhanced contextual conditioning behavior

increased food intake

abnormal response to novel object

abnormal response to social novelty

abnormal motor capabilities/coordination/movement

abnormal reflex

abnormal righting response

limb grasping

tremors

impaired coordination

impaired swimming

decreased vertical activity

increased locomotor activity

hyperactivity

circling

increased stereotypic behavior

hyperresponsive

abnormal social/conspecific interaction behavior

abnormal parental behavior

abnormal maternal nurturing

abnormal nest building behavior

reduced male mating frequency

seizures

absence seizures

Availability

Mouse Genotype

Gabrb3^tm1Geh/Gabrb3^tm1Geh

Gabrb3^tm1Uru/Gabrb3^tm1Uru

Gabrb3^tm2.1Uru/Gabrb3^tm2.1Uru

Gabrb3^tm2.1Geh/Gabrb3^tm2.1Geh
Tg(Syn1-cre)671Jxm/? (conditional)

Gabrb3^tm2.1Geh/Gabrb3^tm2.1Geh
Tg(Camk2a-cre)T29-1Stl/? (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/30/2024 MGI 6.23