Symbol
Name
ID

Fgfr2
fibroblast growth factor receptor 2
MGI:95523

Phenotype annotations related to vision/eye

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes

Shallow orbits

Conjunctivitis

Recurrent corneal erosions

Keratitis

Corneal perforation

Limbal stem cell deficiency

Buphthalmos

Optic atrophy

Optic nerve hypoplasia

Hypertelorism

Hypotelorism

Proptosis

Strabismus

Exodeviation

Hypermetropia

Myopia

Visual impairment

Amblyopia

Visual field defect

Alacrima

Ptosis

Bilateral ptosis

Disease(s) Associated with FGFR2

acrocephalosyndactylia

Antley-Bixler syndrome without disordered steroidogenesis

Beare-Stevenson cutis gyrata syndrome

craniosynostosis

Crouzon syndrome

Jackson-Weiss syndrome

lacrimoauriculodentodigital syndrome 1

Pfeiffer syndrome

Saethre-Chotzen syndrome

Mouse Phenotypes

vision/eye phenotype

shallow orbits

absent exorbital lacrimal gland

abnormal lacrimal gland development

absent lacrimal gland bud

absent lacrimal glands

exophthalmos

ocular hypertelorism

decreased inner canthal distance

absent eyelids

eyelids open at birth

Availability

Mouse Genotype

Fgfr2^m1Sgg/Fgfr2^m1Sgg

Fgfr2^tm1.1Dsn/Fgfr2^tm1.1Dsn

Fgfr2^tm3.1Lni/Fgfr2^tm3.1Lni

Fgfr2^tm3Dsn/Fgfr2^tm3Dsn

Fgfr2^tm4Lni/Fgfr2^tm4Lni

Fgfr2^tm1Schl/Fgfr2⁺

Fgfr2^tm2.3Dsn/Fgfr2⁺

Fgfr2^tm3.1Cxd/Fgfr2⁺

Fgfr2^tm4Lni/Fgfr2⁺

Fgfr2^tm1Dor/Fgfr2^tm1Dor
H2az2^{Tg(Wnt1-cre)11Rth}/H2az2⁺ (conditional)

Fgfr2^tm1Dor/Fgfr2^tm1Dor
Tg(Pax6-cre,GFP)1Pgr/0 (conditional)

Fgfr2^tm1Ewj/Fgfr2⁺
Tg(EIIa-cre)C5379Lmgd/0 (conditional)

Fgfr2^tm2Cxd/Fgfr2⁺
Tg(EIIa-cre)C5379Lmgd/0 (conditional)

Fgfr2^tm2Ewj/Fgfr2⁺
Tg(EIIa-cre)C5379Lmgd/0 (conditional)

Fgfr2^tm3Cxd/Fgfr2⁺
Tg(Col2a1-cre)1Xya/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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