|
Symbol Name ID |
Fgfr2
fibroblast growth factor receptor 2 MGI:95523 |
| Darker colors indicate more annotations |
| Human Phenotypes | Low anterior hairline |
Cutis gyrata of scalp |
Preauricular pit |
Redundant neck skin |
Palmoplantar cutis laxa |
Single transverse palmar crease |
Bilateral single transverse palmar creases |
Breast carcinoma |
Acne |
Abnormal hair pattern |
Hypoplastic fingernail |
Small nail |
Hyperhidrosis |
Hyperextensible skin |
Minimal subcutaneous fat |
Skin tags |
Acanthosis nigricans |
| Disease(s) Associated with FGFR2 | |||||||||||||||||
| acrocephalosyndactylia | |||||||||||||||||
| Beare-Stevenson cutis gyrata syndrome | |||||||||||||||||
| breast cancer | |||||||||||||||||
| craniosynostosis | |||||||||||||||||
| lacrimoauriculodentodigital syndrome 1 | |||||||||||||||||
| Saethre-Chotzen syndrome |
| Mouse Phenotypes | increased keratinocyte proliferation |
abnormal mammary gland bud morphology |
abnormal mammary placode morphology |
absent mammary gland |
decreased sebaceous gland number |
sebaceous gland atrophy |
epidermal cyst |
skin inflammation |
abnormal coat/ hair morphology |
progressive hair loss |
abnormal zigzag hair morphology |
absent hypodermis muscle layer |
abnormal nail morphology |
abnormal hair follicle morphology |
abnormal hair follicle development |
abnormal hair follicle orientation |
decreased hair follicle number |
abnormal vibrissa number |
abnormal hair cycle |
abnormal skin morphology |
abnormal dermis papillary layer morphology |
thin dermal layer |
abnormal epidermal layer morphology |
abnormal epidermis stratum basale morphology |
abnormal epidermis stratum corneum morphology |
parakeratosis |
epidermis stratum granulosum hyperplasia |
epidermis stratum spinosum hyperplasia |
acanthosis |
abnormal keratinocyte morphology |
epidermal hyperplasia |
thick epidermis |
thin epidermis |
translucent skin |
decreased skin pigmentation |
thin skin |
increased skin papilloma incidence |
|
| Availability | Mouse Genotype | |||||||||||||||||||||||||||||||||||||
| Fgfr2tm1.1Dsn/Fgfr2tm1.1Dsn | ||||||||||||||||||||||||||||||||||||||
| Fgfr2tm3Dsn/Fgfr2tm3Dsn | ||||||||||||||||||||||||||||||||||||||
| Fgfr2tm3Ewj/Fgfr2+ | ||||||||||||||||||||||||||||||||||||||
| Fgfr2tm1Dor/Fgfr2tm1Dor Tg(KRT5-cre)5132Jlj/0 (conditional) |
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| Fgfr2tm1Dsn/Fgfr2tm1Dsn Tg(KRT5-cre)5132Jlj/0 (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/16/2024 MGI 6.23 |
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