|
Symbol Name ID |
Ercc2
excision repair cross-complementing rodent repair deficiency, complementation group 2 MGI:95413 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Conjunctival telangiectasia |
Breast carcinoma |
Erythema |
Telangiectasia |
Telangiectasia of the skin |
Jaundice |
Erythroderma |
Alopecia |
Sparse hair |
Pili torti |
Tiger tail banding |
Trichorrhexis nodosa |
Trichoschisis |
Brittle hair |
Fine hair |
Small nail |
Fragile nails |
Nail dystrophy |
Freckling |
Hypermelanotic macule |
Hypopigmented skin patches |
Melanocytic nevus |
Dry skin |
Cutaneous photosensitivity |
Dermal atrophy |
Thin skin |
Macule |
Poikiloderma |
Pterygium |
Thickened skin |
Hyperkeratosis |
Congenital nonbullous ichthyosiform erythroderma |
Basal cell carcinoma |
Papilloma |
Squamous cell carcinoma |
| Disease(s) Associated with ERCC2 | |||||||||||||||||||||||||||||||||||
| breast cancer | |||||||||||||||||||||||||||||||||||
| cerebrooculofacioskeletal syndrome 2 | |||||||||||||||||||||||||||||||||||
| pancreatic cancer | |||||||||||||||||||||||||||||||||||
| photosensitive trichothiodystrophy 1 | |||||||||||||||||||||||||||||||||||
| xeroderma pigmentosum | |||||||||||||||||||||||||||||||||||
| xeroderma pigmentosum group D |
| Mouse Phenotypes | integument phenotype |
abnormal sebaceous gland morphology |
enlarged sebaceous gland |
abnormal coat/ hair morphology |
white spotting |
alopecia |
focal dorsal hair loss |
sparse hair |
brittle hair |
rough coat |
greasy coat |
abnormal hair cuticle |
abnormal hair follicle morphology |
enlarged hair follicles |
hyperkeratosis |
abnormal epidermis stratum granulosum morphology |
acanthosis |
reddish skin |
scaly skin |
skin photosensitivity |
thick skin |
increased skin tumor incidence |
|
| Availability | Mouse Genotype | ||||||||||||||||||||||
| Ercc2Mhdarco15/Ercc2Mhdarco15 | |||||||||||||||||||||||
| Ercc2tm2(ERCC2)Jhjh/Ercc2tm2(ERCC2)Jhjh | |||||||||||||||||||||||
| Ercc2tm3Jhjh/Ercc2tm3Jhjh | * | ||||||||||||||||||||||
| Ercc2tm1Jhjh/Ercc2tm2(ERCC2)Jhjh | |||||||||||||||||||||||
| Ercc2tm1Jmch/Ercc2tm2(ERCC2)Jhjh | |||||||||||||||||||||||
| Ercc2tm2(ERCC2)Jhjh/Ercc2tm2Jmch | * | ||||||||||||||||||||||
| Ercc2tm2(ERCC2)Jhjh/Ercc2tm3Jhjh | * | ||||||||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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