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Symbol
Name
ID
Dlx3
distal-less homeobox 3
MGI:94903
Phenotype annotations related to integument
Darker colors indicate more annotations
Human Phenotypes
Abnormal hair morphology
Abnormal hair quantity
Abnormality of the nail
Fragile nails
Disease(s) Associated with DLX3
trichodontoosseous syndrome

Mouse Phenotypes
enlarged sebaceous gland
alopecia
abnormal hair shaft morphology
abnormal hair follicle morphology
abnormal hair follicle development
accelerated hair follicle regression
increased hair follicle cell proliferation
thick dermal layer
abnormal epidermal layer morphology
epidermal hyperplasia
thick epidermis
Availability Mouse Genotype
Dlx3tm3Mso/Dlx3tm3Mso
Tg(KRT14-cre)#Smr/0  (conditional)
Dlx3tm2Mso/Dlx3tm3Mso
Tg(KRT14-cre)#Smr/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory