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Symbol
Name
ID

Smad4
SMAD family member 4
MGI:894293

Phenotype annotations related to growth/size/body

Darker colors indicate more annotations

Human Phenotypes	Hepatosplenomegaly	Peritoneal abscess	Failure to thrive	Weight loss
Disease(s) Associated with SMAD4	Hepatosplenomegaly	Peritoneal abscess	Failure to thrive	Weight loss
juvenile polyposis syndrome
Lynch syndrome
pancreatic cancer

Mouse Phenotypes		abnormal tooth morphology	small incisors	abnormal enamel morphology	malocclusion	embryonic growth retardation	decreased embryo size	small thoracic cavity	kidney cyst	decreased body size
Availability	Mouse Genotype	abnormal tooth morphology	small incisors	abnormal enamel morphology	malocclusion	embryonic growth retardation	decreased embryo size	small thoracic cavity	kidney cyst	decreased body size
	Smad4^E6sad/Smad4^E6sad
	Smad4^m4Mag/Smad4^m4Mag
	Smad4^tm1Cxd/Smad4^tm1Cxd
	Smad4^tm1Mak/Smad4^tm1Mak
	Smad4^m4Mag/Smad4^tm1Cxd
	Smad4^tm2.1Cxd/Smad4^tm2.1Cxd Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0 (conditional)
	Bmp7^tm6(cre)Rob/Bmp7⁺ Smad4^tm1Rob/Smad4^tm1.1Rob (conditional)
	Smad4^tm2.1Cxd/Smad4⁺ Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/30/2024 MGI 6.23