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Symbol
Name
ID

Cryaa
crystallin, alpha A
MGI:88515

Phenotype annotations related to vision/eye

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes	Microcornea	Cataract	Developmental cataract	Progressive cataract	Iris coloboma	Microphthalmia	Strabismus	Nystagmus	Visual impairment	Amblyopia	Glaucoma
Disease(s) Associated with CRYAA
cataract 9 multiple types

Mouse Phenotypes

vision/eye phenotype

increased lens epithelium apoptosis

increased lens fiber apoptosis

abnormal lens morphology

abnormal lens capsule morphology

ruptured lens capsule

lens vacuoles

abnormal lens epithelium morphology

abnormal lens fiber morphology

cataract

nuclear cataract

small lens

microphthalmia

Availability

Mouse Genotype

Cryaa^2J/Cryaa^2J

Cryaa^2J/Cryaa^2J
Tg(CAG-EGFP)1Osb/0

Cryaa^Aey7/Cryaa^Aey7

Cryaa^L1N/Cryaa^L1N

Cryaa^L1N/Cryaa^L1N
Tg(CAG-EGFP)1Osb/0

*

Cryaa^lop18/Cryaa^lop18

Cryaa^tm1.1Ady/Cryaa^tm1.1Ady

Cryaa^tm1Ady/Cryaa^tm1Ady

Cryaa^tm1Wawr/Cryaa^tm1Wawr

Cryaa^tm2Ady/Cryaa^tm2Ady

*

Cryaa^Aey7/Cryaa⁺

Cryaa^L1N/Cryaa⁺

Cryaa^tm1.1Ady/Cryaa⁺

Cryaa^tm1Ady/Cryaa⁺

Cryaa^tm1Wawr/Cryaa⁺

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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