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Symbol
Name
ID
F2
coagulation factor II
MGI:88380
Phenotype annotations related to skeleton
Darker colors indicate more annotations
Human Phenotypes
Joint hemorrhage
Coronal craniosynostosis
Decreased calvarial ossification
Micrognathia
Malar flattening
Brachydactyly
Abnormality of the elbow
Joint swelling
Bent long bone
Hypoplastic pubic bone
Short clavicles
Bell-shaped thorax
Osteoporosis
Arthritis
Gout
Osteoarthritis
Disease(s) Associated with F2
coronary artery disease
factor VIII deficiency
hemophilia B
pre-eclampsia
prothrombin deficiency
systemic lupus erythematosus

Mouse Phenotypes
decreased susceptibility to induced arthritis
decreased bone mineral content
Availability Mouse Genotype
F2tm1b(EUCOMM)Hmgu/F2+
F2tm2Jld/F2+

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory