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Symbol
Name
ID

Cdk4
cyclin dependent kinase 4
MGI:88357

Phenotype annotations related to homeostasis/metabolism

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes	Decreased resting energy expenditure	Type II diabetes mellitus	Insulin resistance
Disease(s) Associated with CDK4	Decreased resting energy expenditure	Type II diabetes mellitus	Insulin resistance
obesity
type 2 diabetes mellitus

Mouse Phenotypes		homeostasis/metabolism phenotype	hyperglycemia	decreased circulating follicle stimulating hormone level	decreased circulating insulin level	decreased circulating progesterone level	edema	abnormal glucose homeostasis	increased urine glucose level	ketoaciduria
Availability	Mouse Genotype	homeostasis/metabolism phenotype	hyperglycemia	decreased circulating follicle stimulating hormone level	decreased circulating insulin level	decreased circulating progesterone level	edema	abnormal glucose homeostasis	increased urine glucose level	ketoaciduria
	Cdk4^tm1.1Bbd/Cdk4^tm1.1Bbd	*
	Cdk4^{tm1b(NCOM)Mfgc}/Cdk4^{tm1b(NCOM)Mfgc}
	Cdk4^tm1Bbd/Cdk4^tm1Bbd
	Cdk4^tm1Kiyo/Cdk4^tm1Kiyo
	Cdk4^wnch/Cdk4^wnch

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/30/2024 MGI 6.23