Symbol
Name
ID

Cacna1b
calcium channel, voltage-dependent, N type, alpha 1B subunit
MGI:88296

Phenotype annotations related to behavior/neurological

*	Aspects of the system are reported to show a normal phenotype.
!	Indicates phenotype varies with strain background.
	Darker colors indicate more annotations

Mouse Phenotypes

behavior/neurological phenotype

abnormal behavior

abnormal behavioral response to xenobiotic

alcohol aversion

decreased alcohol consumption

enhanced behavioral response to alcohol

impaired behavioral response to alcohol

abnormal learning/memory/conditioning

abnormal conditioned taste aversion behavior

impaired conditioned place preference behavior

abnormal discrimination learning

impaired social transmission of food preference

increased exploration in new environment

abnormal spatial learning

abnormal long-term spatial reference memory

increased aggression towards mice

decreased anxiety-related response

decreased thigmotaxis

hyporesponsive to tactile stimuli

decreased startle reflex

decreased grip strength

abnormal locomotor behavior

abnormal gait

hyperactivity

abnormal sleep duration

abnormal sleep pattern

abnormal frequency of paradoxical sleep

fragmentation of sleep/wake states

abnormal sensory capabilities/reflexes/nociception

increased chemical nociceptive threshold

decreased chemically-elicited antinociception

increased thermal nociceptive threshold

Availability

Mouse Genotype

Cacna1b^tm1.1Dili/Cacna1b^tm1.1Dili

Cacna1b^{tm1b(KOMP)Wtsi}/Cacna1b^{tm1b(KOMP)Wtsi}

Cacna1b^tm1Hssh/Cacna1b^tm1Hssh

Cacna1b^tm1Ksw/Cacna1b^tm1Ksw

Cacna1b^tm1Ttan/Cacna1b^tm1Ttan

Cacna1b^tm2.1Dili/Cacna1b^tm2.1Dili

Tg(Itgam-cre/ERT2,U6-RNAi:Cacna1b)17Ttan/0

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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