Symbol
Name
ID

Ctnnb1
catenin beta 1
MGI:88276

Phenotype annotations related to vision/eye

Darker colors indicate more annotations

Human Phenotypes

Optic atrophy

Retinal degeneration

Retinal detachment

Retinal fold

Retinal hole

Exudative vitreoretinopathy

Strabismus

Nystagmus

Total ophthalmoplegia

Hypermetropia

Diplopia

Progressive visual loss

Disease(s) Associated with CTNNB1

autosomal dominant intellectual developmental disorder 19

exudative vitreoretinopathy 7

medulloblastoma

Mouse Phenotypes

abnormal retina vasculature morphology

increased lens epithelium apoptosis

abnormal eye morphology

abnormal lens capsule morphology

ruptured lens capsule

abnormal lens development

abnormal lens epithelium morphology

disorganized secondary lens fibers

cataract

nuclear cataract

small lens

abnormal optic eminence morphology

abnormal retina development

ocular hypertelorism

microphthalmia

absent eyelids

anophthalmia

Availability

Mouse Genotype

Ctnnb1^Bfc/Ctnnb1⁺

Ctnnb1^em1V/Ctnnb1^em1V
Tg(Pdgfb-icre/ERT2,-EGFP)1Frut/0 (conditional)

Ctnnb1^tm1Mmt/Ctnnb1^tm1Mmt
Tg(Cryaa-cre)10Mlr/0 (conditional)

Ctnnb1^tm2Kem/Ctnnb1^tm2Kem
Tg(Pdgfb-icre/ERT2,-EGFP)1Frut/0 (conditional)

Ctnnb1^tm2Kem/Ctnnb1^tm2Kem
Tg(Tcfap2a-cre)1Will/0 (conditional)

Ctnnb1^tm4Wbm/Ctnnb1^tm4Wbm
Tg(Cryaa-cre)10Mlr/? (conditional)

Ctnnb1^tm4Wbm/Ctnnb1^tm4Wbm
Tg(Cryaa-cre,Tyr)39Mlr/? (conditional)

Ctnnb1^tm1Mmt/Ctnnb1⁺
Tg(Tcfap2a-cre)1Will/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/30/2024 MGI 6.23