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Symbol Name ID |
Ctnnb1
catenin beta 1 MGI:88276 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Breast carcinoma |
Pilomatrixoma |
| Disease(s) Associated with CTNNB1 | ||
| ovarian cancer | ||
| pilomatrixoma |
| Mouse Phenotypes | integument phenotype |
increased hair follicle apoptosis |
increased mammary gland tumor incidence in breeding females |
squamous metaplasia of preputial gland |
abnormal hair follicle melanogenesis |
reduced hair shaft melanin granule number |
abnormal pinna hair pigmentation |
abnormal tail hair pigmentation |
absent coat pigmentation |
diluted coat color |
abnormal hair growth |
alopecia |
focal hair loss |
abnormal hair follicle morphology |
abnormal hair follicle development |
abnormal hair follicle infundibulum morphology |
absent hair follicles |
decreased hair follicle number |
hair follicle degeneration |
absent vibrissae |
loss of vibrissae |
abnormal hair cycle anagen phase |
accelerated hair follicle regression |
abnormal dermis papillary layer morphology |
abnormal epidermal layer morphology |
thick epidermis stratum basale |
thick epidermis suprabasal layer |
abnormal keratinocyte morphology |
thick epidermis |
skin lesions |
skin fibrosis |
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| Availability | Mouse Genotype | |||||||||||||||||||||||||||||||
| Tg(Tyr-Ctnnb1/EGFP)#Lru/0 | ||||||||||||||||||||||||||||||||
| Ctnnb1tm1Mmt/Ctnnb1tm1Mmt Tg(Mx1-cre)1Cgn/0 (conditional) |
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| Ctnnb1tm1Yy/Ctnnb1tm1Yy Tg(Prrx1-cre)1Cjt/0 (conditional) |
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| Ctnnb1tm2Kem/Ctnnb1tm2Kem Tg(KRT5-rtTA)#Glk/0 Tg(tetO-cre)1Jaw/0 (conditional) |
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| Ctnnb1tm2Kem/Ctnnb1tm2Kem Tg(Krt1-15-cre/PGR*)22Cot/0 (conditional) |
* | |||||||||||||||||||||||||||||||
| Ctnnb1tm2Kem/Ctnnb1tm2Kem Tg(KRT14-cre/ERT)20Efu/0 (conditional) |
* | |||||||||||||||||||||||||||||||
| Ctnnb1tm2Kem/Ctnnb1tm2Kem Tg(Tyr-cre)1Lru/0 (conditional) |
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| Ctnnb1tm4Wbm/Ctnnb1tm4Wbm Krt14tm1(cre)Wbm/Krt14+ (conditional) |
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| Ctnnb1tm4Wbm/Ctnnb1tm4Wbm Krt14tm1.1(cre)Wbm/Krt14+ (conditional) |
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| Ctnnb1tm4Wbm/Ctnnb1tm4Wbm Tg(Cryaa-cre)10Mlr/? (conditional) |
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| Ctnnb1tm4Wbm/Ctnnb1tm4Wbm Tg(KRT14-cre)1Efu/0 (conditional) |
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| Ctnnb1tm1Mmt/Ctnnb1+ Tg(Mx1-cre)1Cgn/0 (conditional) |
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| Ctnnb1tm1Mmt/Ctnnb1+ Tg(Pbsn-cre)4Prb/0 (conditional) |
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| Ctnnb1tm1Mmt/Ctnnb1+ Tg(Tcfap2a-cre)1Will/0 (conditional) |
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| Ctnnb1tm1Mmt/Ctnnb1+ Tg(Msx2-rtTA)885Lma/0 Tg(tetO-cre)1Jaw/0 (conditional) |
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| Ctnnb1tm1Mmt/Ctnnb1+ Tg(Wap-cre)11738Mam/0 (conditional) |
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| Ctnnb1tm2Kem/Ctnnb1tm2.1Kem Tg(Foxn1-cre)1Tbo/0 (conditional) |
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| Ctnnb1tm4Wbm/Ctnnb1+ Tg(KRT14-cre)1Efu/0 (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/30/2024 MGI 6.23 |
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