Symbol
Name
ID

Camk2a
calcium/calmodulin-dependent protein kinase II alpha
MGI:88256

Phenotype annotations related to behavior/neurological

*	Aspects of the system are reported to show a normal phenotype.
!	Indicates phenotype varies with strain background.
	Darker colors indicate more annotations

Mouse Phenotypes

behavior/neurological phenotype

abnormal avoidance learning behavior

abnormal contextual conditioning behavior

impaired contextual conditioning behavior

abnormal cued conditioning behavior

impaired long-term object recognition memory

decreased exploration in new environment

abnormal spatial learning

impaired spatial learning

abnormal short-term spatial reference memory

impaired spatial working memory

increased aggression towards mice

decreased depression-related behavior

decreased anxiety-related response

increased thigmotaxis

abnormal response to social novelty

enhanced coordination

abnormal locomotor behavior

increased vertical activity

increased locomotor activity

hyperactivity

circling

abnormal social/conspecific interaction behavior

seizures

sporadic seizures

Availability

Mouse Genotype

Camk2a^em1Rjco/Camk2a^em1Rjco

Camk2a^m1Btlr/Camk2a^m1Btlr

Camk2a^tm1.1Oyam/Camk2a^tm1.1Oyam

Camk2a^tm1Mllr/Camk2a^tm1Mllr

Camk2a^tm1Sva/Camk2a^tm1Sva

Camk2a^tm3Sva/Camk2a^tm3Sva

Camk2a^tm4Sva/Camk2a^tm4Sva

Camk2a^tm5Sva/Camk2a^tm5Sva

Camk2a^em1Rjco/Camk2a⁺

Camk2a^tm1.1Oyam/Camk2a⁺

Camk2a^tm1Sva/Camk2a⁺

Camk2a^tm5Sva/Camk2a⁺

Camk2a^tm1.1Yelg/Camk2a^tm1.1Yelg
Tg(CAG-cre/Esr1*)5Amc/0 (conditional)

Camk2a^tm1.1Yelg/Camk2a^tm1.1Yelg
Emx1^{tm1.1(cre)Ito}/0 (conditional)

Camk2a^tm1.1Yelg/Camk2a^tm1.1Yelg
Tg(Pcp2-cre)2Mpin/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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