|
Symbol Name ID |
C3
complement component 3 MGI:88227 |
| Darker colors indicate more annotations |
| Human Phenotypes | Abnormal erythrocyte enzyme concentration or activity |
Decreased circulating iron concentration |
Unconjugated hyperbilirubinemia |
Increased blood urea nitrogen |
Elevated circulating creatinine concentration |
Reduced haptoglobin level |
Increased circulating lactate dehydrogenase concentration |
Renal Fanconi syndrome |
Fever |
Recurrent fever |
Hematuria |
Pyuria |
Glycosuria |
Proteinuria |
Hemoglobinuria |
Paroxysmal nocturnal hemoglobinuria |
Hemosiderinuria |
| Disease(s) Associated with C3 | |||||||||||||||||
| complement component 3 deficiency | |||||||||||||||||
| paroxysmal nocturnal hemoglobinuria | |||||||||||||||||
| sickle cell anemia | |||||||||||||||||
| systemic lupus erythematosus |
| Mouse Phenotypes | abnormal intestinal lipid absorption |
abnormal blood homeostasis |
increased circulating bilirubin level |
decreased circulating glucose level |
decreased circulating insulin level |
decreased circulating leptin level |
decreased circulating free fatty acids level |
increased circulating free fatty acids level |
decreased circulating triglyceride level |
decreased circulating interleukin-6 level |
decreased circulating tumor necrosis factor level |
decreased circulating alanine transaminase level |
increased circulating alanine transaminase level |
abnormal blood coagulation |
abnormal energy expenditure |
abnormal enzyme/coenzyme level |
abnormal glucose homeostasis |
abnormal lipid homeostasis |
increased triglyceride level |
abnormal tumor necrosis factor level |
decreased urine albumin level |
decreased cerebral infarct size |
decreased susceptibility to injury |
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| Availability | Mouse Genotype | |||||||||||||||||||||||
| C3tm1Crr/C3tm1Crr | ||||||||||||||||||||||||
| C3tm1Hrc/C3tm1Hrc | ||||||||||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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