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Symbol
Name
ID 		Braf
Braf transforming gene
MGI:88190
Phenotype annotations related to behavior/neurological
*Aspects of the system are reported to show a normal phenotype.
!Indicates phenotype varies with strain background.
Darker colors indicate more annotations
Human Phenotypes
Abdominal pain
Anorexia
Feeding difficulties in infancy
Gastrostomy tube feeding in infancy
Nasogastric tube feeding in infancy
Poor suck
Poor appetite
Back pain
Tongue thrusting
Chronic fatigue
Disease(s) Associated with BRAF
cardiofaciocutaneous syndrome
cardiofaciocutaneous syndrome 1
Noonan syndrome 7
pancreatic cancer

Mouse Phenotypes
behavior/neurological phenotype
enhanced behavioral response to xenobiotic
abnormal associative learning
impaired contextual conditioning behavior
impaired long-term object recognition memory
abnormal spatial learning
decreased food intake
increased aggression
excessive scratching
impaired balance
impaired coordination
abnormal locomotor behavior
decreased vertical activity
increased locomotor activity
hyperactivity
abnormal mating frequency
convulsive seizures
Availability Mouse Genotype
Braftm1.1Eyc/Braftm1.1Eyc *
Braftm2.1Eyc/Braftm2.1Eyc *
Braftm1Bbd/Braf+ !
Braftm1Sva/Braftm1Sva
Tg(Camk2a-cre)1557Sva/0  (conditional)
Braftm2.1Urr/Braftm2.1Urr
Tg(Nes-cre)1Kln/0  (conditional)
Braftm2Urr/Braftm2Urr
Tg(Nes-cre)1Kln/0  (conditional)
Braftm1Cpri/Braf+
Scn10atm2(cre)Jwo/Scn10a+  (conditional)		 *
Braftm1Sva/Braftm1.1Sva
Tg(Nes-cre)1Kln/0  (conditional)		 *
Braftm1Tumg/Braf+
Tg(CAG-cre)2Osb/0  (conditional)
Braftm1Wds/Braftm1.1Wds
Tg(Nes-cre)1Kln/0  (conditional)		 *
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory