Symbol
Name
ID

Bmp4
bone morphogenetic protein 4
MGI:88180

Phenotype annotations related to growth/size/body

Darker colors indicate more annotations

Human Phenotypes	Failure to thrive
Disease(s) Associated with BMP4	Failure to thrive
syndromic microphthalmia 6

Mouse Phenotypes

heart right ventricle hypertrophy

nasal bone hypoplasia

short nasal bone

abnormal secondary palate development

palatal shelves fail to meet at midline

decreased palatal shelf size

palatal shelf fusion with tongue or mandible

abnormal face development

cleft palate

abnormal snout morphology

short snout

absent outer ear

embryonic growth retardation

abnormal embryo size

abnormal head mesenchyme morphology

decreased body weight

omphalocele

failure of ventral body wall closure

kidney cyst

polycystic kidney

enlarged kidney

Availability

Mouse Genotype

Bmp4^{tm1b(EUCOMM)Hmgu}/Bmp4^{tm1b(EUCOMM)Hmgu}

Bmp4^tm1Blh/Bmp4^tm1Blh

Bmp4^{tm2(tetO-Bmp4,lacZ)Jfm}/Bmp4^{tm2(tetO-Bmp4,lacZ)Jfm}

Bmp4^tm2Blh/Bmp4^tm2Blh

Bmp4^tm5.1Bhr/Bmp4^tm5.1Bhr

Bmp4^tm1.1Jlch/Bmp4^tm2Blh

Bmp4^tm1Blh/Bmp4⁺

Bmp4^tm2Blh/Bmp4⁺

Bmp4^tm5.1Bhr/Bmp4^tm2.1Blh

Bmp4^tm3Blh/Bmp4^tm3Blh
Foxg1^tm1(cre)Skm/Foxg1⁺ (conditional)

H2az2^{Tg(Wnt1-cre)11Rth}/H2az2⁺
Tg(CAG-Bmp4,-EGFP)1Ypc/0 (conditional)

Osr2^tm2(cre)Jian/Osr2⁺
Tg(CAG-Bmp4,-EGFP)1Ypc/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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