Symbol
Name
ID

Bmp4
bone morphogenetic protein 4
MGI:88180

Phenotype annotations related to embryo

Darker colors indicate more annotations

Mouse Phenotypes

abnormal pharyngeal arch artery morphology

increased metanephric mesenchyme apoptosis

abnormal embryo development

abnormal embryo turning

abnormal mesoderm development

sirenomelia

abnormal rostral-caudal axis patterning

embryonic growth retardation

abnormal embryo size

abnormal embryonic cloaca development

abnormal lateral plate mesoderm morphology

abnormal hindlimb bud morphology

abnormal head mesenchyme morphology

abnormal Wolffian duct morphology

abnormal neural tube closure

abnormal posterior primitive streak morphology

abnormal primitive node morphology

failure of primitive streak formation

abnormal allantois morphology

absent allantois

small allantois

abnormal amniotic cavity morphology

abnormal chorion morphology

abnormal visceral yolk sac morphology

abnormal visceral yolk sac mesenchyme morphology

absent visceral yolk sac blood islands

abnormal extraembryonic mesoderm development

Availability

Mouse Genotype

Bmp4^{tm1b(EUCOMM)Hmgu}/Bmp4^{tm1b(EUCOMM)Hmgu}

Bmp4^tm1Blh/Bmp4^tm1Blh

Bmp4^{tm2(tetO-Bmp4,lacZ)Jfm}/Bmp4^{tm2(tetO-Bmp4,lacZ)Jfm}

Bmp4^tm2Blh/Bmp4^tm2Blh

Bmp4^tm5.1Bhr/Bmp4^tm5.1Bhr

Bmp4^tm1.1Jlch/Bmp4^tm2Blh

Bmp4^tm2Blh/Bmp4⁺

Bmp4^tm5.1Bhr/Bmp4^tm2.1Blh

Bmp4^tm4Blh/Bmp4^tm4Blh
Isl1^tm1(cre)Sev/Isl1⁺ (conditional)

Bmp4^tm1Jfm/Bmp4^tm1.1Jfm
Nkx2-5^tm1(cre)Rjs/Nkx2-5⁺ (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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