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Symbol Name ID |
Atp1a3
ATPase, Na+/K+ transporting, alpha 3 polypeptide MGI:88107 |
| * | Aspects of the system are reported to show a normal phenotype. |
| ! | Indicates phenotype varies with strain background. |
| Darker colors indicate more annotations |
| Human Phenotypes | Drooling |
Anorexia |
Depression |
Emotional lability |
Atypical behavior |
Aggressive behavior |
Impulsivity |
High-pitched cry |
| Disease(s) Associated with ATP1A3 | ||||||||
| alternating hemiplegia of childhood | ||||||||
| developmental and epileptic encephalopathy 99 | ||||||||
| dystonia 12 |
| Mouse Phenotypes | behavior/neurological phenotype |
abnormal behavior |
enhanced behavioral response to addictive substance |
increased susceptibility to pharmacologically induced seizures |
abnormal sensitization to xenobiotic |
impaired passive avoidance behavior |
enhanced conditioned place preference behavior |
impaired contextual conditioning behavior |
abnormal habituation |
abnormal habituation to a new environment |
abnormal long-term object recognition memory |
decreased exploration in new environment |
increased exploration in new environment |
abnormal spatial learning |
impaired spatial learning |
decreased anxiety-related response |
increased thigmotaxis |
increased freezing behavior |
abnormal response to novel object |
abnormal motor capabilities/coordination/movement |
abnormal startle reflex |
limb grasping |
dystonia |
tremors |
ataxia |
enhanced coordination |
impaired coordination |
abnormal locomotor behavior |
abnormal gait |
short stride length |
decreased locomotor activity |
increased locomotor activity |
hyperactivity |
hemiplegia |
hemiparesis |
prolonged circadian behavior period |
abnormal sleep pattern |
abnormal non-rapid eye movement sleep pattern |
abnormal paradoxical sleep pattern |
decreased frequency of paradoxical sleep |
increased thermal nociceptive threshold |
seizures |
abnormal seizure response to inducing agent |
increased kindling response |
environmentally induced seizures |
convulsive seizures |
abnormal spike wave discharge |
|
| Availability | Mouse Genotype | |||||||||||||||||||||||||||||||||||||||||||||||
| Atp1a3Myk/Atp1a3+ | ! | |||||||||||||||||||||||||||||||||||||||||||||||
| Atp1a3Myk/Atp1a3+ Tg(Atp1a3)1Stcl/0 |
* | |||||||||||||||||||||||||||||||||||||||||||||||
| Atp1a3tm1.1Kwk/Atp1a3+ | ||||||||||||||||||||||||||||||||||||||||||||||||
| Atp1a3tm1.1Tmklh/Atp1a3+ | * | |||||||||||||||||||||||||||||||||||||||||||||||
| Atp1a3tm1b(EUCOMM)Hmgu/Atp1a3+ | ||||||||||||||||||||||||||||||||||||||||||||||||
| Atp1a3tm1Ling/Atp1a3+ | ||||||||||||||||||||||||||||||||||||||||||||||||
| Atp1a3tm1Mika/Atp1a3+ | ||||||||||||||||||||||||||||||||||||||||||||||||
| Atp1a3tm1Ute/Atp1a3+ | * | |||||||||||||||||||||||||||||||||||||||||||||||
| Tg(Atp1a3)1Stcl/0 | ||||||||||||||||||||||||||||||||||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/16/2024 MGI 6.23 |
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