|
Symbol Name ID |
App
amyloid beta precursor protein MGI:88059 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Mouse Phenotypes | behavior/neurological phenotype |
lethargy |
decreased susceptibility to pharmacologically induced seizures |
increased susceptibility to pharmacologically induced seizures |
abnormal learning/memory/conditioning |
abnormal active avoidance behavior |
impaired passive avoidance behavior |
abnormal cued conditioning behavior |
abnormal long-term object recognition memory |
abnormal response to new environment |
decreased exploration in new environment |
abnormal spatial learning |
abnormal spatial reference memory |
abnormal long-term spatial reference memory |
impaired spatial working memory |
abnormal emotion/affect behavior |
increased aggression towards mice |
abnormal fear/anxiety-related behavior |
abnormal anxiety-related response |
increased anxiety-related response |
increased thigmotaxis |
abnormal motor capabilities/coordination/movement |
impaired swimming |
decreased grip strength |
abnormal locomotor behavior |
abnormal locomotor activation |
behavioral arrest |
decreased locomotor activity |
increased locomotor activity |
abnormal circadian behavior |
seizures |
clonic seizures |
myoclonus |
tonic-clonic seizures |
|
| Availability | Mouse Genotype | ||||||||||||||||||||||||||||||||||
| Apptm1.1Tcs/Apptm1.1Tcs | * | ||||||||||||||||||||||||||||||||||
| Apptm1Ck/Apptm1Ck | |||||||||||||||||||||||||||||||||||
| Apptm1Cwe/Apptm1Cwe | |||||||||||||||||||||||||||||||||||
| Apptm1Dbo/Apptm1Dbo | |||||||||||||||||||||||||||||||||||
| Apptm1Somm/Apptm1Somm | |||||||||||||||||||||||||||||||||||
| Apptm2.1Tcs/Apptm2.1Tcs | |||||||||||||||||||||||||||||||||||
| Apptm2Umu/Apptm2Umu | * | ||||||||||||||||||||||||||||||||||
| Apptm3.1Tcs/Apptm3.1Tcs | |||||||||||||||||||||||||||||||||||
| Tg(Thy1-App*R609D*K612E)4Vln/Tg(Thy1-App*R609D*K612E)4Vln | |||||||||||||||||||||||||||||||||||
| Tg(Thy1-App*R609D*K612E)6Vln/Tg(Thy1-App*R609D*K612E)6Vln | |||||||||||||||||||||||||||||||||||
| Apptm1b(KOMP)Wtsi/App+ | |||||||||||||||||||||||||||||||||||
| Apptm1Ini/App+ | |||||||||||||||||||||||||||||||||||
| Apptm3.2Umu/Apptm2Cwe | |||||||||||||||||||||||||||||||||||
| Tg(Camk2a-tTA)1Mmay/0 Tg(tetO-APPSwInd)107Dbo/0 |
* | ||||||||||||||||||||||||||||||||||
| Tg(Thy1-App*R609D*K612E)2Vln/0 | |||||||||||||||||||||||||||||||||||
| Tg(Thy1-App*R609D*K612E)4Vln/0 | |||||||||||||||||||||||||||||||||||
| Tg(Thy1-App*R609D*K612E)6Vln/0 | |||||||||||||||||||||||||||||||||||
| Tg(App)1874Kha/? | |||||||||||||||||||||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/30/2024 MGI 6.23 |
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