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Symbol
Name
ID

Apoe
apolipoprotein E
MGI:88057

Phenotype annotations related to muscle

Darker colors indicate more annotations

Human Phenotypes

Foot dorsiflexor weakness

Lower limb muscle weakness

Upper limb muscle weakness

Rigidity

Spasticity

Spastic tetraparesis

Muscle spasm

Fatigable weakness of bulbar muscles

Fatigable weakness of swallowing muscles

Fatigable weakness of respiratory muscles

Generalized muscle weakness

Skeletal muscle atrophy

Progressive distal muscular atrophy

Progressive spinal muscular atrophy

Disease(s) Associated with APOE

Alzheimer's disease 3

amyotrophic lateral sclerosis

exfoliation syndrome

multiple myeloma

Mouse Phenotypes		decreased cardiac muscle triglyceride level	abnormal vascular smooth muscle physiology	abnormal vasodilation	decreased vasodilation	decreased skeletal muscle triglyceride level	impaired muscle relaxation
Availability	Mouse Genotype	decreased cardiac muscle triglyceride level	abnormal vascular smooth muscle physiology	abnormal vasodilation	decreased vasodilation	decreased skeletal muscle triglyceride level	impaired muscle relaxation
	Apoe^tm1Unc/Apoe^tm1Unc
	Apoe^tm1.1Mae/Apoe^tm1.1Mae Tg(Fabp4-cre)1Rev/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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