|
Symbol Name ID |
Apob
apolipoprotein B MGI:88052 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Unconjugated hyperbilirubinemia |
Decreased HDL cholesterol concentration |
Decreased LDL cholesterol concentration |
Increased LDL cholesterol concentration |
Hypercholesterolemia |
Hypocholesterolemia |
Hypertriglyceridemia |
Elevated circulating creatinine concentration |
Elevated circulating alanine aminotransferase concentration |
Elevated circulating aspartate aminotransferase concentration |
Increased circulating lactate dehydrogenase concentration |
Glucose intolerance |
Diabetes mellitus |
Type II diabetes mellitus |
Impaired glucose tolerance |
Insulin resistance |
Reduced circulating vitamin A concentration |
Decreased circulating vitamin E concentration |
Hematuria |
| Disease(s) Associated with APOB | |||||||||||||||||||
| coronary artery disease | |||||||||||||||||||
| familial hypercholesterolemia | |||||||||||||||||||
| familial hypobetalipoproteinemia 1 | |||||||||||||||||||
| sickle cell anemia | |||||||||||||||||||
| type 2 diabetes mellitus |
| Mouse Phenotypes | homeostasis/metabolism phenotype |
abnormal circulating cholesterol level |
abnormal circulating HDL cholesterol level |
decreased circulating HDL cholesterol level |
decreased circulating LDL cholesterol level |
increased circulating LDL cholesterol level |
decreased circulating VLDL cholesterol level |
decreased circulating cholesterol level |
decreased circulating triglyceride level |
increased circulating triglyceride level |
abnormal circulating apolipoprotein level |
abnormal cholesterol homeostasis |
abnormal triglyceride level |
|
| Availability | Mouse Genotype | |||||||||||||
| Apobtm1.1Zc/Apobtm1.1Zc | ||||||||||||||
| Apobtm1Mae/Apobtm1Mae | ||||||||||||||
| Apobtm1Meh/Apobtm1Meh | * | |||||||||||||
| Apobtm1Sgy/Apobtm1Sgy | ||||||||||||||
| Apobtm1Unc/Apobtm1Unc | ||||||||||||||
| Apobtm1Zc/Apobtm1Zc | ||||||||||||||
| Apobtm2Sgy/Apobtm2Sgy | ||||||||||||||
| Apobtm5Sgy/Apobtm5Sgy | ||||||||||||||
| Apobtm1.1Zc/Apob+ | ||||||||||||||
| Apobtm1Mae/Apob+ | ||||||||||||||
| Apobtm1Meh/Apob+ | * | |||||||||||||
| Apobtm1Unc/Apob+ | ||||||||||||||
| Apobtm1Zc/Apob+ | ||||||||||||||
| Apobtm1Zc/Apobtm1.1Zc | ||||||||||||||
| Apobtm2Sgy/Apobtm4Sgy | ||||||||||||||
| Apobtm3Sgy/Apob+ | ||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/30/2024 MGI 6.23 |
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