|
Symbol Name ID |
Apc
APC, WNT signaling pathway regulator MGI:88039 |
| Darker colors indicate more annotations |
| Human Phenotypes | Hepatosplenomegaly |
Peritoneal abscess |
Weight loss |
| Disease(s) Associated with APC | |||
| pancreatic cancer |
| Mouse Phenotypes | absent upper incisors |
abnormal tooth development |
absent teeth |
increased forehead pigmentation |
abnormal ear shape |
increased ear pigmentation |
abnormal embryo size |
decreased embryo size |
ovary cyst |
decreased body weight |
weight loss |
cachexia |
abnormal abdominal wall morphology |
abnormal thoracic cavity morphology |
kidney cyst |
polycystic kidney |
skin cyst |
epidermal cyst |
abnormal head development |
decreased body length |
decreased body size |
postnatal growth retardation |
decreased fetal size |
enlarged kidney |
enlarged liver |
liver hyperplasia |
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| Availability | Mouse Genotype | ||||||||||||||||||||||||||
| ApcMin/ApcMin | |||||||||||||||||||||||||||
| Apctm1Rfo/Apctm1Rfo | |||||||||||||||||||||||||||
| Apctm3Mmt/Apctm3Mmt | |||||||||||||||||||||||||||
| ApcMin/Apc+ | |||||||||||||||||||||||||||
| Apctm1.1Rsmi/Apc+ | |||||||||||||||||||||||||||
| Apctm1Rak/Apc+ | |||||||||||||||||||||||||||
| Apctm2Rfo/Apc+ | |||||||||||||||||||||||||||
| Apctm1Rsmi/Apctm1Rsmi Tg(Col2a1-cre)1Rsjo/0 (conditional) |
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| Apctm1Rsmi/Apctm1Rsmi Pgrtm2(cre)Lyd/Pgr+ (conditional) |
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| Apctm1Tno/Apctm1Tno Tg(Cdh16-cre)91Igr/0 (conditional) |
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| Apctm2.1Cip/Apctm2.1Cip (conditional) | |||||||||||||||||||||||||||
| Apctm2.1Cip/Apctm2.1Cip Tg(Ttr-cre/Esr1*)1Vco/0 (conditional) |
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| Apctm2Rak/Apctm2Rak Tg(KRT14-cre)8Brn/0 (conditional) |
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| Apctm2Rak/Apctm2Rak Tg(Car1-cre)5Flt/0 (conditional) |
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| Apctm1Tno/Apc+ Tg(CDX2-cre)101Erf/0 (conditional) |
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| Apctm1Tno/Apc+ Tg(Vil1-cre)997Gum/0 (conditional) |
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| Apctm2.1Cip/Apc+ Tg(Vil1-cre/ERT2)23Syr/0 (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/16/2024 MGI 6.23 |
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