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Symbol Name ID |
Chrnb2
cholinergic receptor nicotinic beta 2 subunit MGI:87891 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Urinary incontinence |
Attention deficit hyperactivity disorder |
Atypical behavior |
Motor stereotypy |
| Disease(s) Associated with CHRNB2 | ||||
| autosomal dominant nocturnal frontal lobe epilepsy |
| Mouse Phenotypes | behavior/neurological phenotype |
abnormal behavior |
abnormal behavioral response to nicotine |
abnormal associative learning |
impaired passive avoidance behavior |
abnormal habituation to a new environment |
abnormal response to new environment |
enhanced spatial learning |
decreased anxiety-related response |
abnormal response to novelty |
enhanced coordination |
increased locomotor activity |
hyperactivity |
fragmentation of sleep/wake states |
decreased chemically-elicited antinociception |
abnormal social investigation |
seizures |
increased susceptibility to induction of seizure by inducing agent |
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| Availability | Mouse Genotype | ||||||||||||||||||
| Chrnb2tm1.1Cont/Chrnb2tm1.1Cont | |||||||||||||||||||
| Chrnb2tm1Jpc/Chrnb2tm1Jpc | * | ||||||||||||||||||
| Chrnb2tm1.1Cont/Chrnb2+ | |||||||||||||||||||
| Tg(Prnp-tTA)F959Sbp/0 Tg(tetO-Chrnb2*V287L)H3Gica/0 |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 03/24/2026 MGI 6.24 |
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