|
Symbol Name ID |
Ace
angiotensin I converting enzyme MGI:87874 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Increased circulating IgA level |
Increased circulating IgG level |
Decreased circulating antibody level |
Paraproteinemia |
Pedal edema |
Hypercalcemia |
Decreased level of 1,5 anhydroglucitol in serum |
Increased LDL cholesterol concentration |
Hypercholesterolemia |
Hypertriglyceridemia |
Elevated circulating creatinine concentration |
Elevated circulating C-reactive protein concentration |
Elevated circulating amyloid A concentration |
Hyperproteinemia |
Increased CSF protein concentration |
Elevated circulating hepatic transaminase concentration |
Decreased alpha-galactosidase A activity |
Elevated erythrocyte sedimentation rate |
Hyperglycemia |
Glucose intolerance |
Diabetes mellitus |
Type I diabetes mellitus |
Type II diabetes mellitus |
Impaired glucose tolerance |
Insulin resistance |
Ketoacidosis |
Edema |
Joint swelling |
Lymphedema |
Pleural effusion |
Chylothorax |
Pulmonary edema |
Fever |
Recurrent fever |
Hypothermia |
Abnormality of vitamin B12 metabolism |
Elevated circulating globotriaosylceramide concentration |
Hypercalciuria |
Hematuria |
Urinary mulberry cells |
Decreased level of D-mannose in urine |
Increased level of L-fucose in urine |
Proteinuria |
Lipiduria |
Amyloidosis |
Renal amyloidosis |
Ascites |
Scarring |
| Disease(s) Associated with ACE | ||||||||||||||||||||||||||||||||||||||||||||||||
| Behcet's disease | ||||||||||||||||||||||||||||||||||||||||||||||||
| coronary artery disease | ||||||||||||||||||||||||||||||||||||||||||||||||
| Fabry disease | ||||||||||||||||||||||||||||||||||||||||||||||||
| familial mediterranean fever | ||||||||||||||||||||||||||||||||||||||||||||||||
| IgA glomerulonephritis | ||||||||||||||||||||||||||||||||||||||||||||||||
| multiple myeloma | ||||||||||||||||||||||||||||||||||||||||||||||||
| pre-eclampsia | ||||||||||||||||||||||||||||||||||||||||||||||||
| sarcoidosis | ||||||||||||||||||||||||||||||||||||||||||||||||
| stomach cancer | ||||||||||||||||||||||||||||||||||||||||||||||||
| type 1 diabetes mellitus | ||||||||||||||||||||||||||||||||||||||||||||||||
| type 2 diabetes mellitus |
| Mouse Phenotypes | homeostasis/metabolism phenotype |
increased insulin secretion |
abnormal homeostasis |
increased circulating creatinine level |
increased blood urea nitrogen level |
decreased circulating angiotensin II level |
abnormal circulating protein level |
abnormal circulating angiotensinogen level |
decreased circulating angiotensinogen level |
decreased urine aldosterone level |
decreased angiotensin II level |
increased urine potassium level |
abnormal urine homeostasis |
abnormal urine osmolality |
decreased urine osmolality |
abnormal angiotensin I-converting enzyme activity |
decreased angiotensin I-converting enzyme activity |
increased renin activity |
abnormal response/metabolism to endogenous compounds |
decreased susceptibility to injury |
|
| Availability | Mouse Genotype | ||||||||||||||||||||
| Acetm1Keb/Acetm1Keb | |||||||||||||||||||||
| Acetm1Mcf/Acetm1Mcf | |||||||||||||||||||||
| Acetm1Unc/Acetm1Unc | |||||||||||||||||||||
| Acetm2Keb/Acetm2Keb | |||||||||||||||||||||
| Acetm4Keb/Acetm4Keb | |||||||||||||||||||||
| Acetm8.1Keb/Acetm8.1Keb | * | ||||||||||||||||||||
| Acetm8Keb/Acetm8Keb | |||||||||||||||||||||
| Acetm9Keb/Acetm9Keb | * | ||||||||||||||||||||
| Acetm1Unc/Ace+ | * | ||||||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/16/2024 MGI 6.23 |
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