Symbol
Name
ID

Grxcr1
glutaredoxin, cysteine rich 1
MGI:3577767

Phenotype annotations related to hearing/vestibular/ear

Darker colors indicate more annotations

Human Phenotypes	Abnormal vestibular function	Progressive sensorineural hearing impairment	Hearing impairment
Disease(s) Associated with GRXCR1
autosomal recessive nonsyndromic deafness 25

Mouse Phenotypes

abnormal ear morphology

abnormal cochlear hair cell stereociliary bundle morphology

abnormal inner hair cell stereociliary bundle morphology

short inner hair cell stereocilia

abnormal outer hair cell stereociliary bundle morphology

thin cochlear hair cell stereocilia

abnormal cochlear inner hair cell morphology

cochlear hair cell degeneration

abnormal type I vestibular cell

abnormal vestibular hair cell stereociliary bundle morphology

thin vestibular hair cell stereocilia

vestibular hair cell degeneration

abnormal inner ear vestibule morphology

abnormal auditory brainstem response

increased or absent threshold for auditory brainstem response

decreased cochlear nerve compound action potential

impaired hearing

deafness

abnormal vestibular system physiology

Availability

Mouse Genotype

Grxcr1^em1(IMPC)J/Grxcr1^em1(IMPC)J

Grxcr1^mpc265H/Grxcr1^mpc265H

Grxcr1^pi-2J/Grxcr1^pi-2J

Grxcr1^pi-3J/Grxcr1^pi-3J

Grxcr1^pi-4J/Grxcr1^pi-4J

Grxcr1^pi-tde/Grxcr1^pi-tde

Grxcr1^{pi-Tg(Eno2-Gabrb3)0370Brll}/Grxcr1^{pi-Tg(Eno2-Gabrb3)0370Brll}

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/30/2024 MGI 6.23