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Symbol Name ID |
Otulin
OTU deubiquitinase with linear linkage specificity MGI:3577015 |
| Darker colors indicate more annotations |
| Human Phenotypes | Skin rash |
| Disease(s) Associated with OTULIN | |
| otulipenia |
| Mouse Phenotypes | abnormal epidermal stem cell apoptosis |
abnormal keratinocyte differentiation |
abnormal epidermal stem cell proliferation |
sebaceous gland hypertrophy |
epidermal cyst |
impaired skin barrier function |
dermatitis |
epidermal hyperplasia |
skin lesions |
spontaneous skin ulceration |
increased skin squamous cell carcinoma incidence |
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| Availability | Mouse Genotype | |||||||||||
| Otulintm1c(EUCOMM)Hmgu/Otulintm1c(EUCOMM)Hmgu Tg(KRT14-cre)1Cgn/0 (conditional) |
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| Otulinem1Gvl/Otulintm1c(EUCOMM)Hmgu Tg(KRT14-cre)1Cgn/0 (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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