Symbol
Name
ID

Cdsn
corneodesmosin
MGI:3505689

Phenotype annotations related to integument

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes	Sparse scalp hair	Abnormality of the nail
Disease(s) Associated with CDSN	Sparse scalp hair	Abnormality of the nail
hypotrichosis 2

Mouse Phenotypes

integument phenotype

sebaceous gland hypertrophy

dermal cyst

impaired skin barrier function

skin inflammation

alopecia

hairless

abnormal hair shaft morphology

abnormal hair follicle morphology

distended hair follicles

hair follicle degeneration

mixed cellular infiltration to dermis

abnormal epidermal layer morphology

abnormal epidermis stratum corneum morphology

absent epidermis stratum corneum

hyperkeratosis

parakeratosis

abnormal epidermis stratum granulosum morphology

acanthosis

epidermal hyperplasia

scaly skin

spontaneous skin ulceration

abnormal skin condition

psoriasis

increased skin papilloma incidence

decreased skin tensile strength

Availability

Mouse Genotype

Cdsn^tm1Mmat/Cdsn^tm1Mmat

Cdsn^tm1Mmat/Cdsn⁺

Cdsn^tm1.1Ics/Cdsn^tm1.1Ics
Tg(KRT14-cre)1Ipc/0 (conditional)

Cdsn^tm1.1Ics/Cdsn^tm1.1Ics
Tg(KRT14-cre/ERT2)1Ipc/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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