About Help FAQ

Symbol
Name
ID

Tph2
tryptophan hydroxylase 2
MGI:2651811

Phenotype annotations related to homeostasis/metabolism

Darker colors indicate more annotations

Human Phenotypes	Increased serum serotonin
Disease(s) Associated with TPH2	Increased serum serotonin
autistic disorder

Mouse Phenotypes		impaired adaptive thermogenesis	decreased circulating insulin-like growth factor I level	increased core body temperature	abnormal serotonin level	decreased serotonin level
Availability	Mouse Genotype	impaired adaptive thermogenesis	decreased circulating insulin-like growth factor I level	increased core body temperature	abnormal serotonin level	decreased serotonin level
	Tph2^Arg447/Tph2^Arg447
	Tph2^Pro447/Tph2^Pro447
	Tph2^tm1.1Zfc/Tph2^tm1.1Zfc
	Tph2^tm1Bdr/Tph2^tm1Bdr
	Tph2^tm1Dmkh/Tph2^tm1Dmkh
	Tph2^tm1Lex/Tph2^tm1Lex
	Tph2^tm1Mca/Tph2^tm1Mca
	Tph2^tm2.2Pasq/Tph2^tm2.2Pasq
	Tph2^tm1Mca/Tph2⁺
	Tph2^tm2.1Pasq/Tph2^tm2.2Pasq Tg(CMV-cre/ERT)1Ipc/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/30/2024 MGI 6.23