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Name
ID

Frem2
Fras1 related extracellular matrix protein 2
MGI:2444465

Phenotype annotations related to vision/eye

Darker colors indicate more annotations

Human Phenotypes	Microphthalmia	Glaucoma
Disease(s) Associated with FREM2	Microphthalmia	Glaucoma
Fraser syndrome 2
isolated cryptophthalmia

Mouse Phenotypes

corneal vascularization

abnormal eye morphology

abnormal anterior eye segment morphology

absent ciliary body

acoria

iris hypoplasia

iris synechia

abnormal cornea morphology

abnormal lens morphology

abnormal eye development

eye bleb

microphthalmia

abnormal eyelid morphology

cryptophthalmos

increased total retina thickness

anophthalmia

Availability

Mouse Genotype

Frem2^b2b1562Clo/Frem2^b2b1562Clo

Frem2^b2b3270Clo/Frem2^b2b3270Clo

Frem2^em2Hali/Frem2^em2Hali

Frem2^my-F11/Frem2^my-F11

Frem2^my-Ucl/Frem2^my-Ucl

Frem2^my/Frem2^my

Frem2^ne/Frem2^ne

Frem2^em1Hali/Frem2^em2Hali

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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