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Symbol
Name
ID
Dna2
DNA replication helicase/nuclease 2
MGI:2443732
Phenotype annotations related to cellular
Darker colors indicate more annotations
Human Phenotypes
Decreased mitochondrial number
Decreased activity of mitochondrial complex II
Disease(s) Associated with DNA2
autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions 6
mitochondrial myopathy

Mouse Phenotypes
abnormal chromosome morphology
aneuploidy
abnormal telomere morphology
decreased telomere length
abnormal mitosis
chromosomal instability
Availability Mouse Genotype
Dna2tm1.1Lzhg/Dna2+

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory