Symbol
Name
ID

Fscn2
fascin actin-bundling protein 2
MGI:2443337

Phenotype annotations related to hearing/vestibular/ear

Darker colors indicate more annotations

Human Phenotypes	Conductive hearing impairment	Sensorineural hearing impairment
Disease(s) Associated with FSCN2	Conductive hearing impairment	Sensorineural hearing impairment
retinitis pigmentosa

Mouse Phenotypes

abnormal cochlear hair cell stereociliary bundle morphology

decreased inner hair cell stereocilia number

decreased outer hair cell stereocilia number

short cochlear hair cell stereocilia

cochlear outer hair cell degeneration

abnormal cochlear outer hair cell physiology

abnormal auditory brainstem response

increased or absent threshold for auditory brainstem response

decreased distortion product otoacoustic emission amplitude

increased susceptibility to age-related hearing loss

impaired hearing

Availability

Mouse Genotype

Fscn2^ahl8/Fscn2^ahl8

Fscn2^em1Fhan/Fscn2^em1Fhan

Tg(RP24-180N9)2Kjn/0

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/16/2024 MGI 6.23