|
Symbol Name ID |
Mfn2
mitofusin 2 MGI:2442230 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Mouse Phenotypes | cellular phenotype |
increased fetal cardiomyocyte apoptosis |
abnormal sperm mitochondrial sheath morphology |
coiled sperm flagellum |
kinked sperm flagellum |
oligozoospermia |
teratozoospermia |
abnormal sperm head morphology |
abnormal sperm nucleus morphology |
absent sperm head |
abnormal male germ cell morphology |
abnormal spermatid morphology |
abnormal spermatocyte morphology |
decreased male germ cell number |
abnormal endoplasmic reticulum morphology |
abnormal mitochondrial morphology |
increased mitochondrial DNA content |
abnormal neuron mitochondrial morphology |
abnormal autophagy |
increased male germ cell apoptosis |
increased neuron apoptosis |
increased testis apoptosis |
abnormal cellular respiration |
abnormal respiratory electron transport chain |
abnormal mitochondrial ATP synthesis coupled electron transport |
abnormal male germ cell physiology |
abnormal mitochondrial physiology |
increased mitochondrial fission |
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| Availability | Mouse Genotype | ||||||||||||||||||||||||||||
| Mfn2tm1.1Balo/Mfn2tm1.1Balo | |||||||||||||||||||||||||||||
| Mfn2tm1Dcc/Mfn2tm1Dcc | |||||||||||||||||||||||||||||
| Mfn2tm2Dcc/Mfn2tm2Dcc | |||||||||||||||||||||||||||||
| Tg(Mnx1-Mfn2*T105M,-EGFP)1Dcc/Tg(Mnx1-Mfn2*T105M,-EGFP)1Dcc | |||||||||||||||||||||||||||||
| Tg(Mnx1-Mfn2*T105M,-EGFP)1Dcc/0 | |||||||||||||||||||||||||||||
| Mfn2em1Cya/Mfn2em1Cya Tg(Stra8-icre)1Reb/0 (conditional) |
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| Mfn2tm1.1Arte/Mfn2tm1.1Arte Slc6a3tm1(cre)Lrsn/Slc6a3+ (conditional) |
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| Mfn2tm1.1Mzhe/Mfn2tm1.1Mzhe (conditional) | |||||||||||||||||||||||||||||
| Mfn2tm1.1Mzhe/Mfn2tm1.1Mzhe Myl2tm1(cre)Krc/Myl2+ (conditional) |
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| Mfn2tm3Dcc/Mfn2tm3Dcc Tg(Stra8-icre)1Reb/0 (conditional) |
* | ||||||||||||||||||||||||||||
| En1tm2(cre)Wrst/En1+ Mfn2tm1Dcc/Mfn2tm3Dcc (conditional) |
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| Mfn2tm1Dcc/Mfn2tm3Dcc (conditional) | |||||||||||||||||||||||||||||
| Mfn2tm1Dcc/Mfn2tm3Dcc Tg(Pcp2-cre)2Mpin/0 (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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