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Symbol
Name
ID
Flcn
folliculin
MGI:2442184
Phenotype annotations related to neoplasm
Darker colors indicate more annotations
Human Phenotypes
Hereditary nonpolyposis colorectal carcinoma
Colon cancer
Large intestinal polyposis
Neoplasm of the stomach
Uterine leiomyosarcoma
Renal neoplasm
Renal cell carcinoma
Transitional cell carcinoma of the bladder
Trichodiscoma
Cutaneous leiomyoma
Cutaneous leiomyosarcoma
Fibrofolliculoma
Multiple lipomas
Disease(s) Associated with FLCN
Birt-Hogg-Dube syndrome
colorectal cancer
renal cell carcinoma

Mouse Phenotypes
increased incidence of tumors by chemical induction
increased lymphoma incidence
increased renal carcinoma incidence
increased kidney tumor incidence
Availability Mouse Genotype
FlcnGt(RRX115)Byg/Flcn+
Flcntm1Btt/Flcntm1Btt
Tg(Cdh16-cre)91Igr/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory