|
Symbol Name ID |
Wnk1
WNK lysine deficient protein kinase 1 MGI:2442092 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Abnormality of metabolism/homeostasis |
| Disease(s) Associated with WNK1 | |
| hereditary sensory and autonomic neuropathy type 2A |
| Mouse Phenotypes | homeostasis/metabolism phenotype |
pericardial edema |
increased circulating aldosterone level |
decreased circulating potassium level |
hyperkalemia |
increased circulating sodium level |
increased circulating angiotensinogen level |
increased urine aldosterone level |
increased circulating chloride level |
increased urine potassium level |
decreased urine sodium level |
increased urine sodium level |
metabolic acidosis |
abnormal urine homeostasis |
increased urine calcium level |
decreased physiological sensitivity to xenobiotic |
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| Availability | Mouse Genotype | ||||||||||||||||
| Wnk1Gt(OST38262)Lex/Wnk1Gt(OST38262)Lex | |||||||||||||||||
| Wnk1tm1.1Juha/Wnk1tm1.1Juha | |||||||||||||||||
| Wnk1tm2Cihu/Wnk1tm2Cihu | |||||||||||||||||
| Wnk1Gt(OST38262)Lex/Wnk1+ | * | ||||||||||||||||
| Tg(Cdh16-Wnk1*)#Cihu/0 | |||||||||||||||||
| Wnk1tm1Clhu/Wnk1tm1Clhu Tg(Tek-cre)12Flv/0 (conditional) |
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| Wnk1tm2.1Juha/Wnk1+ Tg(Pgk1-cre)1Lni/0 (conditional) |
* | ||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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