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Symbol
Name
ID
Tbx22
T-box 22
MGI:2389465
Phenotype annotations related to craniofacial
Darker colors indicate more annotations
Human Phenotypes
Malar flattening
Flat face
Dimple chin
Ankyloglossia
Abnormal palate morphology
Bifid uvula
Cleft palate
Epicanthus
Disease(s) Associated with TBX22
Abruzzo-Erickson syndrome
X-linked cleft palate with or without ankyloglossia

Mouse Phenotypes
decreased palatine bone horizontal plate size
abnormal vomer bone morphology
small vomer bone
palate bone hypoplasia
persistent oronasal membrane
abnormal palatal rugae morphology
cleft secondary palate
tongue ankylosis
choanal atresia
Availability Mouse Genotype
Tbx22tm1.1Sta/Tbx22tm1.1Sta
Tbx22tm1.1Sta/Y

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory