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Symbol
Name
ID
L2hgdh
L-2-hydroxyglutarate dehydrogenase
MGI:2384968
Phenotype annotations related to behavior/neurological
Darker colors indicate more annotations
Human Phenotypes
Atypical behavior
Disease(s) Associated with L2HGDH
L-2-hydroxyglutaric aciduria

Mouse Phenotypes
increased susceptibility to pharmacologically induced seizures
abnormal habituation
decreased exploration in new environment
impaired spatial learning
abnormal spatial working memory
increased vertical activity
increased locomotor activity
fatigue
Availability Mouse Genotype
L2hgdhem1(IMPC)Tcp/L2hgdhem1(IMPC)Tcp
L2hgdhGt(DC0625)Wtsi/L2hgdhGt(DC0625)Wtsi

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory