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Symbol Name ID |
Slc39a14
solute carrier family 39 (zinc transporter), member 14 MGI:2384851 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Microcephaly |
Secondary microcephaly |
Macrocephaly |
Achilles tendon contracture |
Ankle clonus |
Limb joint contracture |
Scoliosis |
| Disease(s) Associated with SLC39A14 | |||||||
| hypermanganesemia with dystonia 2 |
| Mouse Phenotypes | skeleton phenotype |
abnormal osteoblast physiology |
increased osteoclast cell number |
increased femur compact bone thickness |
decreased diameter of femur |
short femur |
abnormal tibia morphology |
decreased diameter of tibia |
short tibia |
decreased length of long bones |
scoliosis |
decreased bone mineral density |
decreased trabecular bone volume |
increased trabecular bone volume |
decreased bone volume |
abnormal compact bone morphology |
decreased bone trabecula number |
increased bone trabecula number |
decreased bone trabecular spacing |
increased bone trabecular spacing |
decreased trabecular bone connectivity density |
decreased trabecular bone mass |
increased trabecular bone thickness |
osteoporosis |
abnormal chondrocyte differentiation |
decreased bone mineralization |
increased bone mineralization |
decreased bone ossification |
increased bone ossification |
decreased femur stiffness |
fragile skeleton |
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| Availability | Mouse Genotype | |||||||||||||||||||||||||||||||
| Slc39a14tm1Lex/Slc39a14tm1Lex | * | |||||||||||||||||||||||||||||||
| Slc39a14tm1Thir/Slc39a14tm1Thir | ||||||||||||||||||||||||||||||||
| Gt(ROSA)26Sortm1(CAG-Slc39a14*L438R)Wvh/Gt(ROSA)26Sor+ Tg(Runx2-icre)1Jtuc/0 (conditional) |
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| Gt(ROSA)26Sortm1(CAG-Slc39a14*L438R)Wvh/Gt(ROSA)26Sor+ Tg(Ctsk-cre)1Rda/0 (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/07/2024 MGI 6.23 |
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