Symbol
Name
ID

Trpv3
transient receptor potential cation channel, subfamily V, member 3
MGI:2181407

Phenotype annotations related to integument

Darker colors indicate more annotations

Human Phenotypes

Palmoplantar keratoderma

Patchy palmoplantar hyperkeratosis

Alopecia universalis

Sparse hair

Subungual hyperkeratosis

Nail dysplasia

Nail dystrophy

Hyperhidrosis

Hyperparakeratosis

Periorificial hyperkeratosis

Orthokeratosis

Parakeratosis

Pruritus

Disease(s) Associated with TRPV3

autosomal dominant mutilating palmoplantar keratoderma with periorificial keratotic plaques

focal nonepidermolytic palmoplantar keratoderma 2

Mouse Phenotypes

dermatitis

erythroderma

abnormal coat/ hair morphology

abnormal hair growth

waved hair

abnormal hair follicle orientation

curly vibrissae

abnormal epidermis stratum corneum morphology

abnormal corneocyte envelope morphology

dry skin

scaly skin

abnormal keratinocyte physiology

Availability

Mouse Genotype

Trpv3^tm1.2Clph/Trpv3^tm1.2Clph

Trpv3^tm1Apat/Trpv3^tm1Apat

Trpv3^Nh/Trpv3⁺

Tg(KRT14-cre)1Amc/0
Trpv3^tm1.1Clph/Trpv3^tm1.1Clph (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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