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Symbol Name ID |
Fcgr4
Fc receptor, IgG, low affinity IV MGI:2179523 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Trismus |
Recurrent sinusitis |
Interphalangeal joint erosions |
Swan neck-like deformities of the fingers |
Dupuytren contracture |
Limited elbow movement |
Joint swelling |
Limited shoulder movement |
Joint stiffness |
Stiff interphalangeal joints |
Osteoporosis |
Arthritis |
Gout |
Rheumatoid arthritis |
Polyarticular arthritis |
Digital flexor tenosynovitis |
| Disease(s) Associated with FCGR3A | ||||||||||||||||
| Behcet's disease | ||||||||||||||||
| coronary artery disease | ||||||||||||||||
| graft-versus-host disease | ||||||||||||||||
| immunodeficiency 20 | ||||||||||||||||
| rheumatoid arthritis | ||||||||||||||||
| systemic lupus erythematosus | ||||||||||||||||
| temporal arteritis |
| Mouse Phenotypes | skeleton phenotype |
decreased osteoclast cell number |
decreased susceptibility to induced arthritis |
arthritis |
decreased bone resorption |
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| Availability | Mouse Genotype | |||||
| Fcgr4tm1.1Rav/Fcgr4tm1.1Rav | ||||||
| Fcgr4tm1Rav/Fcgr4tm1Rav Tg(Ctsk-cre)1Rda/0 (conditional) |
* | |||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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