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Symbol
Name
ID

Pfn3
profilin 3
MGI:2178800

Phenotype annotations related to cellular

Darker colors indicate more annotations

Mouse Phenotypes

abnormal sperm flagellum morphology

abnormal sperm connecting piece morphology

abnormal sperm midpiece morphology

abnormal sperm mitochondrial sheath morphology

necrospermia

oligozoospermia

abnormal sperm head morphology

abnormal acrosome morphology

abnormal acrosome assembly

abnormal proacrosomal vesicle fusion

globozoospermia

detached acrosome

abnormal sperm nucleus morphology

abnormal manchette assembly

abnormal Golgi apparatus morphology

impaired autophagy

decreased sperm progressive motility

asthenozoospermia

abnormal Golgi vesicle transport

Availability

Mouse Genotype

Pfn3^em1Hsc/Pfn3^em1Hsc

Pfn3^em2Hsc/Pfn3^em2Hsc

Pfn3^em3Hsc/Pfn3^em3Hsc

Pfn3^em1Hsc/Pfn3⁺

Pfn3^em2Hsc/Pfn3⁺

Pfn3^em3Hsc/Pfn3⁺

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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