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Symbol
Name
ID 		Dicer1
dicer 1, ribonuclease type III
MGI:2177178
Phenotype annotations related to skeleton
Darker colors indicate more annotations

Mouse Phenotypes
abnormal craniofacial bone morphology
abnormal basicranium morphology
abnormal basisphenoid bone morphology
abnormal frontal bone morphology
frontal bossing
absent alisphenoid bone
absent orbitosphenoid bone
absent presphenoid bone
absent temporal bone squamous part
small neurocranium
shallow orbits
small mandible
abnormal maxillary frontal process morphology
micrognathia
absent palatine bone
small vomer bone
absent zygomatic bone
increased susceptibility to induced arthritis
abnormal long bone morphology
kyphosis
abnormal bone structure
abnormal bone marrow morphology
increased compact bone volume
decreased osteoblast cell number
abnormal cartilage morphology
abnormal skeleton development
delayed endochondral bone ossification
Availability Mouse Genotype
Dicer1tm1Bdh/Dicer1tm1Bdh
Tg(Prrx1-cre)1Cjt/0  (conditional)
Dicer1tm1Bdh/Dicer1tm1Bdh
Tg(Foxp3-EGFP/icre)1aJbs/0  (conditional)
Dicer1tm1Bdh/Dicer1tm1Bdh
H2az2Tg(Wnt1-cre)11Rth/H2az2+  (conditional)
Dicer1tm1Bdh/Dicer1tm1Bdh
Tg(Pax2-cre)1Akg/0  (conditional)
Dicer1tm1Mmk/Dicer1tm1Mmk
Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0  (conditional)
Dicer1tm1Mmk/Dicer1tm1Mmk
Tg(BGLAP-cre)1Clem/0  (conditional)
Dicer1tm1Tara/Dicer1tm1Tara
Foxn1tm3(cre)Nrm/Foxn1+  (conditional)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory