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Symbol
Name
ID

Dicer1
dicer 1, ribonuclease type III
MGI:2177178

Phenotype annotations related to muscle

Darker colors indicate more annotations

Human Phenotypes	Rhabdomyosarcoma	Alveolar rhabdomyosarcoma
Disease(s) Associated with DICER1	Rhabdomyosarcoma	Alveolar rhabdomyosarcoma
DICER1 syndrome
multinodular goiter

Mouse Phenotypes		abnormal myocardium layer morphology	abnormal myocardial fiber morphology	thin ventricle myocardium compact layer	disorganized myocardium	dilated cardiomyopathy	decreased cardiac muscle contractility	increased cardiomyocyte apoptosis	abnormal sarcomere morphology	impaired skeletal muscle regeneration
Availability	Mouse Genotype	abnormal myocardium layer morphology	abnormal myocardial fiber morphology	thin ventricle myocardium compact layer	disorganized myocardium	dilated cardiomyopathy	decreased cardiac muscle contractility	increased cardiomyocyte apoptosis	abnormal sarcomere morphology	impaired skeletal muscle regeneration
	Dicer1^tm1Bdh/Dicer1^tm1Bdh Nkx2-5^tm1(cre)Rjs/Nkx2-5⁺ (conditional)
	Dicer1^tm1Bdh/Dicer1^tm1Bdh Tg(CAG-cre/Esr1*)5Amc/0 (conditional)
	Dicer1^tm1Bdh/Dicer1^tm1Bdh Nkx2-5^tm2(cre)Rph/Nkx2-5⁺ (conditional)
	Dicer1^tm1Smr/Dicer1^tm1Smr Tg(Myh6-cre)2182Mds/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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