|
Symbol Name ID |
Tmprss3
transmembrane protease, serine 3 MGI:2155445 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Sensorineural hearing impairment |
| Disease(s) Associated with TMPRSS3 | |
| autosomal recessive nonsyndromic deafness 8 |
| Mouse Phenotypes | hearing/vestibular/ear phenotype |
abnormal kinocilium morphology |
abnormal cochlea morphology |
absent cochlear hair cells |
absent cochlear inner hair cells |
absent cochlear outer hair cells |
abnormal inner hair cell stereociliary bundle morphology |
abnormal outer hair cell stereociliary bundle morphology |
cochlear inner hair cell degeneration |
cochlear outer hair cell degeneration |
cochlear hair cell degeneration |
abnormal organ of Corti morphology |
organ of Corti degeneration |
abnormal stria vascularis morphology |
absent vestibular hair cells |
vestibular hair cell degeneration |
abnormal vestibular saccule morphology |
increased or absent threshold for auditory brainstem response |
absent distortion product otoacoustic emissions |
deafness |
abnormal vestibular system physiology |
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| Availability | Mouse Genotype | |||||||||||||||||||||
| Tmprss3m1Ingm/Tmprss3m1Ingm | * | |||||||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/30/2024 MGI 6.23 |
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