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Symbol
Name
ID
Ift140
intraflagellar transport 140
MGI:2146906
Phenotype annotations related to cellular
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations

Mouse Phenotypes
cellular phenotype
abnormal sperm flagellum morphology
abnormal outer dense fiber morphology
abnormal sperm axoneme morphology
abnormal sperm end piece morphology
abnormal sperm mitochondrial sheath morphology
abnormal sperm fibrous sheath morphology
kinked sperm flagellum
short sperm flagellum
abnormal primary cilium morphology
decreased kidney epithelial cell primary cilium length
oligozoospermia
teratozoospermia
abnormal sperm head morphology
abnormal sperm nucleus morphology
abnormal spermatid morphology
abnormal manchette morphology
increased kidney apoptosis
decreased sperm progressive motility
asthenozoospermia
immotile sperm
increased kidney cell proliferation
Availability Mouse Genotype
Ift140cauli/Ift140cauli
Ift140tm1c(KOMP)Wtsi/Ift140tm1c(KOMP)Wtsi
Tg(Stra8-icre)1Reb/0  (conditional)
Ift140tm1b(KOMP)Wtsi/Ift140tm1c(KOMP)Wtsi
Tg(Hoxb7-cre)13Amc/?  (conditional)
*

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory